3 Message from Susan Thornton, CEO 4 Board of Directors and Team Members 5 Our Reach 6 Programs & Services 8 Research 9 Alliances 10 Finances 12 Donors 15 Looking Ahead What is Cutaneous Lymphoma? Cutaneous lymphomas are cancers of lymphocytes (white blood cells) that primarily involve the skin. Classification is based upon lymphocyte type: B-lymphocytes (B-cell) or T-lymphocytes (T-cell). Cutaneous T-cell lymphoma (CTCL) is the most common type of cutaneous lymphoma that typically presents with red, scaly patches or thickened plaques of skin that often mimic eczema or chronic dermatitis. Progression from limited skin involvement is variable and may be accompanied by tumor formation, ulceration, and exfoliation, complicated by itching and infections. Advanced stages are defined by involvement of lymph nodes, peripheral blood, and internal organs. Cutaneous lymphomas affect thousands of individuals worldwide. It is estimated that over 30,000 people in the United States alone have been diagnosed with some form of lymphoma. The incidence of cutaneous T-cell lymphoma in the United States is increasing with approximately 3,000 new cases being diagnosed annually. Due to the difficulty of diagnosing the disease in its early stages and the current lack of an accurate reporting system, prevalence of cutaneous lymphoma is thought to be much higher.